Dan Cohen is a partner at stockmatusow and entrepreneur in the fields of nanotechnology, medical diagnostics, and energy storage. Cambridge, Massachusetts-based Crisprs lead asset CTX001 is in development for two indications beta thalassemia and sickle cell disease in collaboration with Vertex Pharma. Now, let's take a speculative twist in our discussion about acquisitions. One of the hot topics in the biopharmaceutical world are mergers & acquisitions (M&A). Earlier, Merck acquired erstwhile Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 billion to build its rare diseases portfolio. 5. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the development of Intravascular Lithotripsy (IVL) to treat severely calcified cardiovascular disease, today announced it has entered into a definitive agreement to acquire Neovasc Inc. (NASDAQ,TSX:NVCN), a company focused on the minimally invasive treatment of refractory angina. Given that the FDA is yet to approve a NASH drug, it is worth taking a risk with this one-trick pony. The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. The Motley Fool recommends Biogen and Gilead Sciences. CRISPRs lead product candidate, CTX001, is an investigational, autologous, gene-edited hematopoietic stem cell therapy that is being evaluated for the treatment of transfusion-dependent beta thalassemia (TDT) and severe sickle cell disease (SCD). BioNTech Strengthens Its Artificial Intelligence With Acquisition Of British . But the way I see it, there's plenty of biotechs in the sea to reinvest those profits. Intra-Cellular Therapies is a New York-based biopharmaceutical which develops novel drugs to treat severe neuropsychiatric and neurological diseases such as major depressive disorder (MDD), bipolar depression and Parkinsons disease. Brian Orelli: I'd like to see Bristol-Myers Squibb (BMY -0.28%) acquire Seagen (SGEN -1.71%). Dan utilizes his experience reading and reviewing scientific literature to evaluate prospects for success. Mergers & Acquisitions (M&As) are back in focus in the biotech sector as Merck MRK recently acquired Acceleron Pharma for $180 per share in cash for an approximate total equity value of $11.5 . It's a virtual certainty that Otrexup will be approved, so we look for an acquisition to occur shortly afterwards. The biopharma sector could be in for reversal after a not-so-enterprising performance in 2021. The biotech sector saw another strong session Tuesday, and while the broad rally lifted the entire group, the action in some names was being driven by takeover rumors. The Company submitted a Marketing Authorization Application to the. Someone is "mistaken" here. ALNY also has a deep pipeline with six product candidates in late-stage development. Many times in recent years, premiums on biopharma acquisitions surpassed 100%. I think Adicet might be a good fit for Gilead, as it's developing off-the-shelf CAR-T therapies. The top ten deals in the industry totaled $97 billion in 2020, led by the $39-billion buyout of Alexion Pharmaceuticals ( ALXN) - Get Free Report late in the year by AstraZeneca ( AZN) - Get Free. Click to get this free report Alnylam Pharmaceuticals, Inc. (ALNY) : Free Stock Analysis Report Biogen Inc. (BIIB) : Free Stock Analysis Report BioMarin Pharmaceutical Inc. (BMRN) : Free Stock Analysis Report Adaptimmune Therapeutics PLC (ADAP) : Free Stock Analysis Report CRISPR Therapeutics AG (CRSP) : Free Stock Analysis Report To read this article on Zacks.com click here. These ASOs regulate the expression of a specific factor, which if present causes a particular disease. Clovis leading drug Rubraca (rucaparib), a poly (ADP-ribose) polymerase (PARP) inhibitor, has been approved by the FDA for the treatment of ovarian and prostate cancer. I have no business relationship with any company whose stock is mentioned in this article. 4. Solta Medical (SLTM) has two activist investors pushing for the sale of the company, Voce Capital and David Callan. Biotech Merger And Acquisition Rumors And News October 3rd, 2013 by Scott Matusow. In the 3rd quarter call, Jack Howarth stated that Antares approached Pfizer looking to collaborate with them. Beginning on February 10, 2012, Voce Capital sent a letter to the Obagi Board of Directors criticizing the Board's adoption of a poison pill and demanding immediate action to address the company's corporate governance failures. In 2003, Alnylam merged with the German pharmaceutical company, Ribopharma AG. They just revealed what they believe are the ten best stocks for investors to buy right now and Bristol Myers Squibb wasn't one of them! (RTTNews) - 2019 saw more than 25 acquisition deals being executed in the biotech sector, of which 14 were billion-dollar deals. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. Acquisition rumors have swirled around specialty biotech BioMarin Pharmaceutical (NASDAQ: BMRN) for years now.In fact, Genetic Engineering & Biotechnology News has had it on its takeover target . It is focused on developing transformative gene-based medicines for serious diseases using its proprietary CRISPR/Cas9 platform. We at Biotech Investments see several catalysts that could make Intra-Cellular Therapies an interesting acquisition target. Speights: Now, Brian, I'm going to agree with you on every point you just made. BioNTech SE (Nasdaq: BNTX, "BioNTech") and InstaDeep Ltd. ("InstaDeep") today announced that they have entered into an agreement under which BioNTech will acquire InstaDeep, a leading global technology company in the field of artificial intelligence ("AI") and machine learning ("ML"). The opinions expressed in this article are those of the writer, subject to the InvestorPlace.comPublishing Guidelines. Is It Too Late to Buy Vertex Pharmaceuticals Stock? Healthcare. 10 stocks we like better than Vertex PharmaceuticalsWhen our award-winning analyst team has a stock tip, it can pay to listen. He utilizes a combination of technical analysis, deep scientific research, and macro views to generate alpha for the team. 1125 N. Charles St, Baltimore, MD 21201. Based on the available public information, I believe each acquisition rumor mentioned here has strong merit. Written by Scott Matusow. Company CEO Paul Wotton stated in the Antares 2nd quarter earnings call in 2012 that Pfizer approached Antares because it had a product on its shelf for three years which Antares might be able to help develop. BioMarin remains on track to submit a Biologics License Application for Valoctocogene roxaparvovec to the FDA by the end of this year. I think that would potentially drive sales of Opdivo. Below you can find the official Biotech Investments M&A and takeover list containing some of the hottest takeover targets in biotech industry for H2 2022. Someone is "mistaken" here. The first few months lived up to expectations: All of the top 10 M&A deals of January-June 2018 exceeded $1.5 billion, paced by the completion of Bayer's $63 billion buyout of Monsanto . 8. Rubraca competes with other PARP inhibitors like Lynparza and Zejula. I don't know, maybe they could out-license those. The rumor involved Pfizer (PFE) being the acquirer. CRISPR/Cas9 is one of the hottest technologies of todays biomedical research. Global Blood Therapeutics ( GBT) - $9B. Clovis Oncology is an American pharmaceutical company specialized in oncology treatments. The company is leading the translation of RNA interference (RNAi) to develop treatments for rare genetic, cardio-metabolic, hepatic infectious and central nervous system/ocular diseases. The quest behind the drive is to fill potential gaps in the pipeline. Mergers and acquisition (M&A) activity in India is heating up. Places you can follow Scott are: www.stockmatusow.com www.twitter.com/StockMatusow @StockMatusow http://www.facebook.com/TheScottMatusowShow Places to follow Dan are: https://twitter.com/biosleuth. The stock has rallied from a little over $1 a share to a current price of $28.84, which represents an increase of over 2800% - a staggering number. Rumors. Like the Medicines Co., Amarin also has a heart drug by the name Vascepa in its kitty. Do Not Sell My Personal Information (CA Residents Only). But there are some deals that Motley Fool contributors Brian Orelli and Keith Speights hope will happen. Vertex and Regeneron would be the most likely to acquire their CRISPR-focused biotech. Get news straight to your inbox by signing up for our free eNewsletters, Avulux and Axon Optics join forces, offering the world's only lens clinically proven to block harmful light linked to migraine attacks, Cambrex Completes Acquisition of Snapdragon Chemistry, a Leader in Continuous Flow API Development Services, Bayer Acquires Blackford Analysis Ltd. Bolstering the Companys Position in Digital Medical Imaging, Leap Jumps Ahead in Cancer Game with Flame Merger, Elicio Therapeutics Enters Into Merger Agreement with Angion Biomedica, Leap Therapeutics Acquires Flame Biosciences, Calyxt and Cibus Announce the Signing of a Definitive Merger Agreement, Ra Medical Systems Realigns Its Board of Directors, Shockwave Medical Announces Agreement to Acquire Neovasc, Calyxt and Cibus Announce Definitive Merger Agreement to Create Industry-Leading Precision Gene Editing and Trait Licensing Company, Aegis Sciences Corporation Acquires HealthTrackRxs Toxicology Business Unit, Elicio Therapeutics and Angion Enter into Definitive Merger Agreement, How to Prepare if Your Company is Being Acquired, Calibre Scientific Acquires Glass Chemicals, a Comprehensive Provider of Laboratory Consumables, Equipment and Services in Spain. The surge in transactions in the pharmaceutical industry saw 16 deals during 2022 - seemingly the largest number in a decade, worth several billion dollars in value. 6 min read Merger and acquisitions (M&A) have been tepid so far in 2020. I own Seagen. However, the Company has turned down Elliott's recommendation. Biotech/FDA. Keep track of M&A as it happens with this database. Keith Speights: Let's switch gears. Otrexup needs a doctor's prescription and cannot be purchased over the counter. Scott has had the most success in trading/investing in smaller cap growth companies. 11. Get biopharma news like this in your inbox daily. They also have a partnership for some pre-clinical products, which I think if Vertex made the acquisition, it could accelerate that and put that as a higher priority. 3 Top Stocks to Buy Now and Hold Forever, Warren Buffett Is Raking in $4.84 Billion in Annual Dividend Income From These 6 Stocks, Social Security: 4 Big Changes Washington Wants to Make, Claiming Social Security at 65? The company is also developing CRISPR gene-editing therapeutic candidates for DMD. 13. In the business of drug development, deals can be just as important as scientific breakthroughs. Nasdaq Pharma giant Pfizer recently announced that it will acquire Arena Pharmaceuticals for $100 per share or a total equity value of approximately $6.7 billion to further expand its portfolio. Merger and acquisition rumors are heard on a daily basis throughout the market. Best Stocks & ETFs. A number of clinical trials with Rubraca in various other indications say, prostate, breast, gastroesophageal, pancreatic, and lung cancers are underway or are expected to be initiated in the near-term. Sanofi has been quite active on the M&A front this year. 2. These symbols will be available throughout the site during your session. Copy and paste multiple symbols separated by spaces. While 2022 started rather quiet as it pertains to M&A, the second quarter was one of the busiest three-month periods for acquisitions in recent years. Ipsen bought out Tercica for $404M, or a 104% premium over the current stock price. GLOBAL MARKETS-Stocks buoyed by cheery data after BOJ damp squib, Nouriel Roubini: There's a massive disconnect between markets and the Fed, U.S. natgas price slump pushes 'widow maker' toward unusual contango, Germany must speed hydrogen plans this year - gas pipeline group OGE, Ian Bremmer: We're in a hot war with Russia. 9. 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