Feeder food: Grain and birdseed. ( Returnto the corrected sentence.). The enzyme eventually builds to normal levels in most children and to almost normal levels in those like Benjy, who carry one gene. Due to all this inbreeding, there were a lot of blue people running around the backwoods of Kentucky. We see fit that they will grow up to be strong holler girls or boys. 3. Cawein would have no part of it, and he related with glee the news that a film crew sent to Kentucky from Hollywood fled the two mean dogs in every front yard without any film. It was real bad in her, Alva Stacy, the boys father, explained. The Faces of Appalachia. the blue color was gone from their skin," Cawein said. At 30%, nausea, difficulty breathing, and an elevated heart rate start to appear. Her name was Ruth Pendergrass, and she had been trying to stir up medical interest in the blue people ever since a dark blue woman walked into the county health department one bitterly cold afternoon and asked for a blood test. She has lived in the primitive dwelling without running water or electricity on the slopes of Dead Fall Mountain her entire life. Stacys son has built a modern house next door, but the old logger wont hear of leaving the cabin he built with timber he personally cut and hewed for Luna and their 13 children. When they settled this country back then, there was no roads. GreenPower Motor Co. to begin manufacturing at South Charleston, West Virginia facility 'this quarter' Hot and cold: Up and down weather calls for adaptation for West Virginia's ski destinations; Morgantown (West Virginia) business owner who pleaded guilty to Jan. 6 charges sued along with Trump; This Week in West Virginia History In the Inuit communities, scientists had pinpointed the problem, a deficiency of an enzyme that converted methemoglobin to hemoglobin. Laughing, the Informant launched into a story of the "West Virginia Blue People", a story about a genetic condition the resulted from intermarriage. New Martinsville has the 2nd most places to buy guns, the 2nd most fishing/bait shops and several places to get chew. 2017-2018 Blue Book Frontice (p. I-VIII) Section 1: Executive (p. 1-330) Section 2: Legislative (p. 331-508) When Two Strangers Lost the Genetic Lottery Martin Fugate arrived in the unsettled frontier of Kentucky in 1820. On a hypothesis, he gave a substance called methylene blue to family members who were willing to take it. Elizabeth had pale white skin, almost translucent. Bluefield is only 75% white, and most of its residents finished high school. So I brought back the new blood and set up my enzyme assay, Cawein continued. Howells Pawn and Guns, New Martinsville, WV. A stance in favor of new abortion restrictions. Having blue children did not concern them. It was almost purple, his father recalls. The Blue Fugates have essentially now gone from reality to legend. Save my name, email, and website in this browser for the next time I comment. My grandmother Luna on my dads side was a blue Fugate. Intermarrying with people other than close relatives meant the likelihood of any Fugate descendant being born with the condition reduced. Benjy was a pretty big item in the hospital, his mother says with a grin. While in the hills, Cawein drove over to see Zach (Big Man) Fugate, the 76-year-old patriarch of the clan on Troublesome Creek. When you look at the numbers, its clear that most of Moundsville is a buncha fun-lovin rednecks. It's a vote cast not just out of allegiance. The female's primary color is light cinnamon with darker-colored wings. The blue Fugates who did not wish to remain blue continued to take the pills, and contacted Dr. Cawein and other doctors to get more of them when needed. The Blue Ridge Mountains are a physiographic province of the larger Appalachian Mountains range. Despite those incredible odds, this is exactly what happened with the Fugates. Her name was Ruth Pendergrass, and she had been trying to stir up medical interest in the blue people ever since a dark blue woman walked into the county health department one bitterly cold afternoon and asked for a blood test. Note: In this instance the reason for cyanosis was not methemoglobinemia but Rh incompatibility. But as Kentucky became more populated and more genes came into the Fugate family tree, there were far fewer children born blue. She looked like she was having a heart attack. The reasons for this almost have to do entirely with coal. The West Virginia motto is Montani semper liberi, and the state is one of the most mountainous in the country; sometimes it is called the "little Switzerland" of America, and once I heard an irreverent local citizen call it the "Afghanistan of the United States."The precipitous upland nature of the terrain makes naturally for three things: (1) poor communications; (2) fierce sectionalism; (3 . If you stayed awake in high-school biology, you might remember that blood is red because red blood cells are packed with proteins called hemoglobin. They were bluern hell, Cawein says. Oh, and they had blue skin. Steelworkers Damion Elkins, 50, right, and Edward Clonch, 43, left, in Huntington West Virginia. Typically, the blue is isolated to one part of the body. Buckhannon is a town thats 95% white, where 3 out of 10 people didnt graduate from high school. The 2010 survey revealed that there were 1,852,994 people living in West Virginia, which represented a modest rise of just 2.5% on the numbers declared at the 2000 census. And shop at Walmart. They were delighted., They changed colors! remembered Pendergrass. West Virginia Get facts and photos about the 35th state. They are known for being carriers of a genetic trait that led to the blood disorder methemoglobinemia, causing the skin to appear blue. Many is more accurate since the practice is legal, or legal under certain circumstances, in more than 20 states. Because the boy was intensely blue at birth but then recovered his normal skin tones, Benjy is assumed to have inherlted only one gene for the condition. It is bordered by Pennsylvania to the north, Maryland and Virginia to the east, Kentucky to the southwest, and Ohio to the northwest. The notion of widespread inbreeding was at least in part the result of crude assumptions about how these isolated forest people might have been perpetuating their communities. Excise tax on bottled soft drinks, syrups and dry mixtures; disposition thereof. Because the Fugate family lived in such an isolated part of the Kentucky, they intermarried with a neighboring family for generations which led to a relatively pure gene pool where the met-H gene appeared much more frequently. This publication also contains information on state and federal agencies; postal information; the Constitutions of the United States and West Virginia; and, considerable information on counties, municipalities and various organizations. They wouldnt come into the waiting room. Tests for abnormal hemoglobin were negative. That total makes West Virginia the 38th most populous state in the country. Population: 7,164 Mobile home parks per capita: 2nd in West Virginia Bars per capita: 2nd in the state Walmart rank: 3rd Elkins is way out in the middle of nowhere south of Morgantown, at the base of the Appalachians. The Blue Ridge Mountains In West Virginia Were Named One Of The 50 Most Beautiful Places In The World We all know the Blue Ridge Mountains in West Virginia are stunning, and it's about time the rest of the world took notice. Dr. Cawein injected the dye into the volunteers, and they were amazed to see how quickly their skin changed from blue to a healthy pink, then gradually to a Caucasian white. All he needed was a substance that could "donate" a free electron to the methemoglobin, allowing it to bond with oxygen. Published November 21, 2021 Updated November 29, 2021 For nearly 200 years, the Fugates known as the blue people of Kentucky remained largely sealed off from the outside world as they passed their blue skin from generation to generation. Methemoglobin which is blue, is a nonfunctional form of the red hemoglobin that carries oxygen. The condition is called methemoglobinemia, which is a disorder that reduces the amount of oxygen in the blood and body tissues, therefore making the skin appear blue. Cawein, Madison and E.J. There was always speculation in the hollows about what made the blue people blue: heart disease, a lung disorder, the possibility proposed by one old-timer that their blood is just a little closer to their skin. But no one knew for sure, and doctors rarely paid visits to the remote creekside settlements where most of the blue Fugates lived until well into the 1950s. martin fugate was blue from birth, which has nothing to do with inbreeding. But his first love, which he developed as an Army medical technician in World War II, was hematology. It can make a claim that it should top this list, since it has the most people. I couldnt tell you what caused it.. Today I have a healthy son/nephew who is slightly green in skincolor. (Baltimore: Gateway Press 1986). Please copy/paste the following text to properly cite this HowStuffWorks.com article: Dave Roos All them old fellers way back then was blue. Trudging up and down the hollows, fending off the two mean dogs that everyone had in their front yard, the doctor and the nurse would spot someone at the top of a hill who looked blue and take off in wild pursuit. All rights reserved. Wingspan: 6.3-8.3 in (Black-Capped), 5.9-7.9 in (Carolina) Chickadees are tiny little birds that are very easy to recognize because of their "black cap" and black bib. It would be hard to doubt this gracious man except that you cant find another person who knew Luna who doesnt remember her as being blue. It run in that generation who lived up and down Ball [Creek]., They looked like anybody else, cept they had the blue color, Stacy says, sitting in a chair in his plaid flannel shirt and suspenders, next to a cardboard box where a small black piglet, kept as a pet, is squealing for his bottle. Luna Stacy possessed the good health common to the blue people, bearing at least 13 children before she died at 84. But Cawein knew from earlier studies that the body has an alternative method of converting methemoglobin back to normal. Legend has it that Martin himself may have had a blue tinge to his skin, but not the dark blue color of later Fugates. It was hard to get out, so they intermarried, says Dennis Stacy, a 51-year-old coal miner and amateur genealogist who has filled a loose-leaf notebook with the laboriously traced blood lines of several local families. Well, according to the official bible of literature, the Merriam-Webster Dictionary, a redneck is: A white person who lives in a small town or in the country especially in the southern U.S., who typically has a working-class job, and who is seen by others as being uneducated and having opinions and attitudes that are offensive.. Of their seven children, four were blue. And by God, they didnt have the enzyme diaphorase. Have you ever heard of the blue people of Kentucky? Blood cells always looked so beautiful to me, he says. As travel became easier, more people moved into and out of the Fugates area of Kentucky, including some actual Fugates. We do not feel less-fortunate. John Stacy still lives on Lick Branch of Ball Creek. The doctor was recently approached by the producers of the television show Thats Incredible. They wanted to parade the blue people across the screen in their weekly display of human oddities. It is home to so much creativity, and has been a place of devastating poverty. Somebody with only one gene would not have the condition but could pass the gene to a child. February 16, 2012 by Tap Vann. I looked at other enzymes and nothing was wrong with them. The Fugate family of Kentucky once lived in the isolated community of Troublesome Creek. If enough blood is "infected" with this faulty type of hemoglobin, it changes from red to an almost purple-ish dark blue. Several familes moved elsewhere after being bought out. One could inherit the gene, not get the blood disorder, but pass the gene on to a child. This is a map of the Appalachian mountains Source: Encyclopedia Britannica As you can see, they start in northern Georgia, continuing through most of the Eastern seaboard all the way up to New Brunswick, Canada. The entry was on the blue men, not of West Virginia, but of the Mountain State's neighbor, Kentucky, . This results in brown blood giving Caucasian patients a bluish hue to their skin. Chapter 1: The Climate of Post-War America Chapter 2: West Virginia - The Violent Heritage Chapter 3: Political Maneuvering Chapter 4: The Creative Act of 1919 Chapter 5: Getting Organized PART II Chapter 6: The Mine Wars, 1919-1929 Chapter 7: Depression and Recovery, 1929-1939 Chapter 8: War Service, 1939-1949 The condition that made the Fugates blue causes large amounts of methemoglobin (which is a blue type of hemoglobin) to circulate in the blood. "Within a few minutes. Blah. The gold of the helmet did not reflect the gold utilized in our colors today. Many of us have college degrees, are nurses, teachers, preachers and well-educated women. The 76-year-old diva used the less than divine choice of words for the Mountain State in a Twitter against Sen. Joe Manchin torpedoing President Biden's multitrillion-dollar spending plans. Legend has it that Martin himself may have had a blue tinge to his skin, but not the dark blue color of later Fugates. She was as blue a woman as I ever saw.. I can see that old blue running out of my skin, he confided. 3 of 10 isnt good enough; think of how high you wouldve finished on this list had more of you ditched class to head to the hills on Friday mornings like a lot of your friends. Written family records do not indicate Martin's skin color, but family legend says he was blue. The condition was clearly genetic, but the key for Cawein was reading reports of hereditary methemoglobinemia among isolated Inuit populations in Alaska where blood relatives often married. If theyd immigrated to other areas, even other areas of Kentucky, they likely would have married non-relatives, and the condition would have faded out of the family long before it did. In 1980, a counter-intuitive solution was discovered where the blue person drinks a chemical-filled solution that is itself blue. If this conversion continued, all the bodys hemoglobin would eventually be rendered useless. What neither she nor Martin could have known is that they both carried the recessive gene for a rare hereditary blood disorder called methemoglobinemia. When Benjy was born with purple skin, his relatives told the perplexed doctors about his great grandmother Luna Fugate. Houses belonging to people that lived in the valley were mostly torn down. Start your free trial today to learn more about your ancestors using our powerful and intuitive search. Just like the Alaskans, their blood had accumulated so much of the blue molecule that it over- whelmed the red of normal hcmoglobin that shows through as pink in the skin of most Caucasians. So close! Published. He married Elizabeth Smith, who carried a recessive gene for a genetic condition called methemoglobinemia, which gives those who have it blue-toned skin, even though they are otherwise perfectly healthy. Elkins is way out in the middle of nowhere south of Morgantown, at the base of the Appalachians. Others, however, did not like being blue, and it was these Fugates, who didnt like their blue coloring, who were the first to volunteer for Caweins experimental treatments. The good news for those who may still be born expressing the blue gene is that there is a treatment. Informant: "So, what my brother told me is that there's a story that there are people in the Appalachian Mountains in West Virginia, near the campus I guess, and there is skin is blue. he passed the gene on to his children. They werent sick; it was just the way they look. What he got from Martin Fugate was dark blue skin. Cawein cheers their bad luck not out of malice but out of a deep respect for the blue people of Troublesome Creek. He tested first for abnormal hemoglobin, but the results were negative. Madison Cawein began hearing rumors about the blue people when he went to work at the University of Kentuckys Lexington medical clinic in 1960. Eventually, a nurse named Ruth Pendergrass heard of them, and, along with a hematologist named Madison Cawein III, decided to go meet these locally famous blue people in person. This small enclave was no longer isolated and they began to disperse and marry outside of their little clan diminishing the effect of the "blue" gene. One day, one of the older mountain men cornered the doctor. The blood disorder is inherited as a simple recessive trait - meaning that to get the disorder, a person would have to inherit two genes, one from each parent. The last known "blue" Fugate descendant was born in 1975. The methylene blue he used on them is a dye a blue dye, ironically. We threw a lot of criteria at this one in order to get the best, most complete results possible. 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